[CA11] Following Route on E80/E120 MFDs

I have an E80 (nav station) and E120 (helm) networked via SeaTalk-hs. Also have autopilot. I’m able to create routes, but the “follow route” and “follow route options” buttons are unavailable. In order to “follow route” and, presumably, use autopilot, does the boat have to be underway? If not, how do I select “follow route”. Thanks!